Hormonal Health

Ngenla

Somatrogon · Solution for injection in pre-filled pen

A long-acting growth hormone given once weekly for growth hormone deficiency in children.

Partner pharmacy
Personal assistance
Discreet delivery

Active ingredient
Somatrogon
Administration
Subcutaneous, once weekly

Shipping & Delivery

Normally dispatched within 24 hours of payment confirmation.
UPS Express · A$25 · Approx. 7–9 business days
Registered Mail · A$15 · Approx. 14–20 business days

Overview

What Ngenla is

Ngenla contains somatrogon, a long-acting recombinant human growth hormone. It is given as a once-weekly injection for the treatment of children and adolescents with growth disturbance due to growth hormone deficiency.

Suitability and dosing are decided by a prescriber on the basis of the approved product information.

How it works

Growth hormone, once a week

Somatrogon is recombinant human growth hormone joined to short peptide sequences taken from human chorionic gonadotropin. These extend its half-life, which allows one injection a week instead of daily injections.

Growth hormone receptorStimulates growth and IGF-1 production.

Extended half-lifeOnce-weekly injection.

In the pivotal phase 3 trial in children with growth hormone deficiency, weekly somatrogon was non-inferior to daily somatropin for height velocity at 12 months.¹

Safety

Side effects and warnings

Commonly reported side effects include:

Injection-site reactions
Headache and fever
Changes in thyroid function, which are monitored

ImportantMust not be used once the growth plates have closed or with active cancer. Treatment is started and monitored by a specialist. Always read the patient information leaflet.

Documents

Product information

Patient information leafletNgenla pre-filled pen · electronic medicines compendiumemc Summary of Product CharacteristicsNgenla pre-filled pen · electronic medicines compendiumemc

FAQ

Common questions

Do I need a prescription?

Ngenla is a prescription-only medicine. After your request, the partner pharmacy verifies whether and how supply is possible, for example through an existing prescription or an assessment by an independent doctor where permitted.

Who is it for?

Children and adolescents with growth disturbance due to insufficient growth hormone, as set out in the product information. Treatment is started by a specialist.

How is it different from daily growth hormone?

The growth hormone effect is the same; the longer half-life allows one injection a week instead of one a day.

Do I pay when I send a request?

No. Payment is arranged individually with customer service once your request has been reviewed and can proceed.

References

Sources

Deal CL, et al. Somatrogon growth hormone in the treatment of pediatric growth hormone deficiency: results of the pivotal pediatric phase 3 clinical trial. J Clin Endocrinol Metab. 2022;107:e2717–e2728.
Ngenla: Summary of Product Characteristics. Pfizer.