{"id":61,"date":"2026-09-30T19:46:23","date_gmt":"2026-09-30T23:46:23","guid":{"rendered":"https:\/\/novameds.health\/ca\/product\/zepbound\/"},"modified":"2026-10-01T12:53:56","modified_gmt":"2026-10-01T16:53:56","slug":"zepbound","status":"publish","type":"product","link":"https:\/\/novameds.health\/ca\/product\/zepbound\/","title":{"rendered":"Zepbound"},"content":{"rendered":"\n<section id=\"overview\" data-nav=\"Overview\"><span class=\"kicker\">Overview<\/span><h2>What Zepbound is<\/h2><p>Zepbound contains tirzepatide, the same active ingredient as Mounjaro. In the US it is authorized for chronic weight management in adults with obesity, or with overweight and at least one weight-related condition, and for moderate to severe obstructive sleep apnea in adults with obesity. It is given as a once-weekly injection under the skin.<\/p><p>As of September 2026 we found no UK marketing authorization for Zepbound; in the UK, tirzepatide is supplied as Mounjaro. Suitability and dosing are decided by a prescriber on the basis of the approved product information.<\/p><\/section>\n<section id=\"how\" data-nav=\"How it works\"><span class=\"kicker\">How it works<\/span><h2>GIP and GLP\u20111, <em>one weekly injection<\/em><\/h2><p>Tirzepatide acts on the receptors of two gut hormones released after meals, GIP and GLP\u20111. Together these effects reduce appetite and food intake, slow gastric emptying and improve blood glucose control.<\/p><div class=\"mech\"><div><b>GIP receptor<\/b><span>Glucose-dependent insulin release; contributes to appetite regulation.<\/span><\/div><div><b>GLP\u20111 receptor<\/b><span>Less hunger, more fullness, slower gastric emptying.<\/span><\/div><\/div><p>In SURMOUNT-1, adults with obesity or overweight without diabetes lost substantially more weight with tirzepatide than with placebo over 72 weeks.<sup><a href=\"#references\">1<\/a><\/sup> In SURMOUNT-OSA, it reduced the severity of obstructive sleep apnea in adults with obesity.<sup><a href=\"#references\">2<\/a><\/sup><\/p><\/section>\n<section id=\"safety\" data-nav=\"Safety\"><span class=\"kicker\">Safety<\/span><h2>Side effects and warnings<\/h2><p>The most commonly reported side effects are gastrointestinal:<\/p><ul class=\"bul\"><li>Nausea, diarrhea, vomiting, constipation and abdominal pain, mostly while the dose is being increased<\/li><li>Reduced appetite, indigestion and injection-site reactions<\/li><li>Gallbladder problems, including gallstones<\/li><\/ul><div class=\"warn\"><svg class=\"icon\" aria-hidden=\"true\"><use href=\"#i-alert\"\/><\/svg><div><strong>Important<\/strong>Seek medical help promptly for severe, persistent abdominal pain, which may be a sign of pancreatitis. Not for use during pregnancy. Always read the patient information leaflet.<\/div><\/div><\/section>\n<section id=\"documents\" data-nav=\"Documents\"><span class=\"kicker\">Documents<\/span><h2>Product information<\/h2><div class=\"docs\"><div class=\"doc-row\"><span class=\"ico\"><svg class=\"icon\" aria-hidden=\"true\"><use href=\"#i-file\"\/><\/svg><\/span><span>Patient information leaflet<small>Supplied by the partner pharmacy<\/small><\/span><\/div><div class=\"doc-row\"><span class=\"ico\"><svg class=\"icon\" aria-hidden=\"true\"><use href=\"#i-file\"\/><\/svg><\/span><span>Summary of Product Characteristics<small>Official product information<\/small><\/span><\/div><\/div><\/section>\n<section id=\"faq\" data-nav=\"FAQ\"><span class=\"kicker\">FAQ<\/span><h2>Common questions<\/h2><div class=\"faq\" style=\"margin-top:18px\"><details open><summary>Do I need a prescription?<svg class=\"icon\" aria-hidden=\"true\"><use href=\"#i-plus\"\/><\/svg><\/summary><p>Zepbound is a prescription-only medicine. After your request, the partner pharmacy verifies whether and how supply is possible, for example through an existing prescription or an assessment by an independent doctor where permitted.<\/p><\/details><details><summary>How is it different from Mounjaro?<svg class=\"icon\" aria-hidden=\"true\"><use href=\"#i-plus\"\/><\/svg><\/summary><p>The active ingredient is the same. In the US, Mounjaro is authorized for type 2 diabetes and Zepbound for weight management and obstructive sleep apnea, each with its own product information.<\/p><\/details><details><summary>Is Zepbound available in the UK?<svg class=\"icon\" aria-hidden=\"true\"><use href=\"#i-plus\"\/><\/svg><\/summary><p>As of September 2026 we found no UK marketing authorization for Zepbound. In the UK, tirzepatide is authorized as Mounjaro, including for weight management.<\/p><\/details><details><summary>Why is the dose increased gradually?<svg class=\"icon\" aria-hidden=\"true\"><use href=\"#i-plus\"\/><\/svg><\/summary><p>Starting low and increasing step by step helps to reduce gastrointestinal side effects. The schedule is set out in the product information and is decided by the prescriber.<\/p><\/details><details><summary>Do I pay when I send a request?<svg class=\"icon\" aria-hidden=\"true\"><use href=\"#i-plus\"\/><\/svg><\/summary><p>No. Payment is arranged individually with customer service once your request has been reviewed and can proceed.<\/p><\/details><\/div><\/section>\n<section id=\"references\" data-nav=\"References\"><span class=\"kicker\">References<\/span><h2>Sources<\/h2><ol class=\"refs\"><li><span>Jastreboff AM, et al. Tirzepatide once weekly for the treatment of obesity (SURMOUNT-1). <i>N Engl J Med<\/i>. 2022;387:205\u2013216.<\/span><\/li><li><span>Malhotra A, et al. Tirzepatide for the treatment of obstructive sleep apnea and obesity (SURMOUNT-OSA). <i>N Engl J Med<\/i>. 2024;391:1193\u20131205.<\/span><\/li><li><span>Zepbound: Prescribing Information. Eli Lilly.<\/span><\/li><\/ol><\/section>\n","protected":false},"excerpt":{"rendered":"<p>Tirzepatide for weight management, marketed under the Zepbound brand.<\/p>\n<p class=\"nm-research-disclaimer\">For research use only. Not intended for human or animal consumption, nor for medical, personal or diagnostic use. By purchasing this product, you confirm that you are qualified to handle research materials.<\/p>\n","protected":false},"featured_media":193,"comment_status":"open","ping_status":"closed","template":"","meta":[],"product_brand":[],"product_cat":[35,32,23],"product_tag":[41],"nm_classification":[],"class_list":["post-61","product","type-product","status-publish","has-post-thumbnail","product_cat-hormones-weight-body-composition","product_cat-peptides","product_cat-weight-management-metabolism","product_tag-prescription","first","instock","shipping-taxable","purchasable","product-type-variable"],"_links":{"self":[{"href":"https:\/\/novameds.health\/ca\/wp-json\/wp\/v2\/product\/61","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/novameds.health\/ca\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/novameds.health\/ca\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/novameds.health\/ca\/wp-json\/wp\/v2\/comments?post=61"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/novameds.health\/ca\/wp-json\/wp\/v2\/media\/193"}],"wp:attachment":[{"href":"https:\/\/novameds.health\/ca\/wp-json\/wp\/v2\/media?parent=61"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/novameds.health\/ca\/wp-json\/wp\/v2\/product_brand?post=61"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/novameds.health\/ca\/wp-json\/wp\/v2\/product_cat?post=61"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/novameds.health\/ca\/wp-json\/wp\/v2\/product_tag?post=61"},{"taxonomy":"nm_classification","embeddable":true,"href":"https:\/\/novameds.health\/ca\/wp-json\/wp\/v2\/nm_classification?post=61"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}