{"id":113,"date":"2026-09-30T19:46:25","date_gmt":"2026-09-30T23:46:25","guid":{"rendered":"https:\/\/novameds.health\/ca\/product\/metformin\/"},"modified":"2026-10-01T11:31:36","modified_gmt":"2026-10-01T15:31:36","slug":"metformin","status":"publish","type":"product","link":"https:\/\/novameds.health\/ca\/product\/metformin\/","title":{"rendered":"Metformin"},"content":{"rendered":"\n<section id=\"overview\" data-nav=\"Overview\"><span class=\"kicker\">Overview<\/span><h2>What Metformin is<\/h2><p>Metformin is a biguanide that lowers blood glucose, mainly by reducing glucose production in the liver and improving insulin sensitivity. It is a first-line medicine for type 2 diabetes.<\/p><p>Suitability and dosing are decided by a prescriber on the basis of the approved product information.<\/p><\/section>\n<section id=\"how\" data-nav=\"How it works\"><span class=\"kicker\">How it works<\/span><h2>Less glucose from the liver, <em>better insulin action<\/em><\/h2><p>Metformin lowers blood glucose mainly by reducing the amount of glucose produced by the liver. It also improves the body\u2019s response to insulin and slows glucose absorption from the gut. Because it does not stimulate insulin release, on its own it rarely causes low blood sugar.<\/p><div class=\"mech\"><div><b>Liver<\/b><span>Less glucose production.<\/span><\/div><div><b>Muscle and gut<\/b><span>Better insulin sensitivity; slower glucose absorption.<\/span><\/div><\/div><p>In UKPDS 34, overweight people with type 2 diabetes treated with metformin had fewer diabetes-related complications than those on conventional treatment.<sup><a href=\"#references\">1<\/a><\/sup><\/p><\/section>\n<section id=\"safety\" data-nav=\"Safety\"><span class=\"kicker\">Safety<\/span><h2>Side effects and warnings<\/h2><p>Commonly reported side effects are gastrointestinal, especially at the start:<\/p><ul class=\"bul\"><li>Nausea, diarrhea, abdominal pain and loss of appetite<\/li><li>A metallic taste<\/li><li>Lower vitamin B12 levels with long-term use<\/li><\/ul><div class=\"warn\"><svg class=\"icon\" aria-hidden=\"true\"><use href=\"#i-alert\"\/><\/svg><div><strong>Important<\/strong>Lactic acidosis is a rare but serious complication, more likely with reduced kidney function or dehydration: kidney function is checked regularly, and treatment may be paused around surgery or contrast X-ray examinations. Always read the patient information leaflet.<\/div><\/div><\/section>\n<section id=\"documents\" data-nav=\"Documents\"><span class=\"kicker\">Documents<\/span><h2>Product information<\/h2><div class=\"docs\"><div class=\"doc-row\"><span class=\"ico\"><svg class=\"icon\" aria-hidden=\"true\"><use href=\"#i-file\"\/><\/svg><\/span><span>Patient information leaflet<small>Supplied by the partner pharmacy<\/small><\/span><\/div><div class=\"doc-row\"><span class=\"ico\"><svg class=\"icon\" aria-hidden=\"true\"><use href=\"#i-file\"\/><\/svg><\/span><span>Summary of Product Characteristics<small>Official product information<\/small><\/span><\/div><\/div><\/section>\n<section id=\"faq\" data-nav=\"FAQ\"><span class=\"kicker\">FAQ<\/span><h2>Common questions<\/h2><div class=\"faq\" style=\"margin-top:18px\"><details open><summary>Do I need a prescription?<svg class=\"icon\" aria-hidden=\"true\"><use href=\"#i-plus\"\/><\/svg><\/summary><p>Metformin is a prescription-only medicine. After your request, the partner pharmacy verifies whether and how supply is possible, for example through an existing prescription or an assessment by an independent doctor where permitted.<\/p><\/details><details><summary>Can it cause low blood sugar?<svg class=\"icon\" aria-hidden=\"true\"><use href=\"#i-plus\"\/><\/svg><\/summary><p>On its own, rarely. The risk increases when it is combined with insulin or medicines that stimulate insulin release, such as sulfonylureas.<\/p><\/details><details><summary>Why is kidney function checked?<svg class=\"icon\" aria-hidden=\"true\"><use href=\"#i-plus\"\/><\/svg><\/summary><p>Metformin is cleared by the kidneys. Reduced kidney function increases the risk of lactic acidosis, so the dose is adjusted or treatment stopped as set out in the product information.<\/p><\/details><details><summary>Do I pay when I send a request?<svg class=\"icon\" aria-hidden=\"true\"><use href=\"#i-plus\"\/><\/svg><\/summary><p>No. Payment is arranged individually with customer service once your request has been reviewed and can proceed.<\/p><\/details><\/div><\/section>\n<section id=\"references\" data-nav=\"References\"><span class=\"kicker\">References<\/span><h2>Sources<\/h2><ol class=\"refs\"><li><span>UK Prospective Diabetes Study (UKPDS) Group. Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). <i>Lancet<\/i>. 1998;352:854\u2013865.<\/span><\/li><li><span>Metformin hydrochloride tablets: Summary of Product Characteristics.<\/span><\/li><\/ol><\/section>\n","protected":false},"excerpt":{"rendered":"<p>A biguanide medicine used as a first-line treatment for type 2 diabetes.<\/p>\n","protected":false},"featured_media":205,"comment_status":"open","ping_status":"closed","template":"","meta":[],"product_brand":[],"product_cat":[23],"product_tag":[41],"nm_classification":[],"class_list":["post-113","product","type-product","status-publish","has-post-thumbnail","product_cat-weight-management-metabolism","product_tag-prescription","first","instock","shipping-taxable","product-type-variable"],"_links":{"self":[{"href":"https:\/\/novameds.health\/ca\/wp-json\/wp\/v2\/product\/113","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/novameds.health\/ca\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/novameds.health\/ca\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/novameds.health\/ca\/wp-json\/wp\/v2\/comments?post=113"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/novameds.health\/ca\/wp-json\/wp\/v2\/media\/205"}],"wp:attachment":[{"href":"https:\/\/novameds.health\/ca\/wp-json\/wp\/v2\/media?parent=113"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/novameds.health\/ca\/wp-json\/wp\/v2\/product_brand?post=113"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/novameds.health\/ca\/wp-json\/wp\/v2\/product_cat?post=113"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/novameds.health\/ca\/wp-json\/wp\/v2\/product_tag?post=113"},{"taxonomy":"nm_classification","embeddable":true,"href":"https:\/\/novameds.health\/ca\/wp-json\/wp\/v2\/nm_classification?post=113"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}